Cannabis can help with depression through a number of cannabinoids and terpenes that work together through the Entourage Effect. One of the main ways cannabis combats depression is due to the positive effect CBD has on the production of serotonin by acting on the 5HT1A receptors in the brain. This effect is amplified by terpenes such as limonene and caryophyllene. 

THC, on its own, acts on the CB1/CB2 receptors, creating a buffer against depression due to its psychoactive effect (in low to medium doses). Together, THC and CBD can alleviate the major symptoms of depression like; insomnia, fatigue, loss of appetite and chronic pain.

According to the World Health Organisation (WHO more than 300 million people across the world experience depression. If you’re experiencing anxiety, low self-esteem, chronic stress and or a lack of appetite and sleep, there is a distinct possibility that you could be one of those millions who is currently fighting depression.

But have you considered the possibility that medical marijuana could actually be used to treat depression?

The common symptoms of depression include continuous low mood or sadness, feeling hopeless and helpless, having low self-esteem and or feelings of anxiety.

While pharmaceutical drugs remain the most common treatments for depression, many more people are now considering several alternatives like medical cannabis. 

Indeed, in recent years, a growing body of scientific research has come to light, indicating strongly that medical marijuana has serious potential in helping to reduce the symptoms related to depression.

Research Highlights the Efficacy of Cannabis as a Treatment for Depression

The fascinating world of cannabis health continues to arouse the curiosity of scientists around the globe. As such, it was only natural for them to study the potential effects and medical benefits that medical cannabis could have when used as a treatment for the depression crisis that seems to be engulfing so much of our planet.

In September of 2019, a study published in the Journal of Affective Disorders, suggested that inhaling cannabis can significantly reduce short-term levels of depression. Of those taking part in the analysis, 89.3% experienced a significant reduction in feelings of depression. 

The analysis also revealed that cannabis was effective in reducing anxiety (over the short-term) and stress. Another study conducted in 2014 was carried out to understand the effects of CBD, one of the dominant cannabinoids in the cannabis plant. The analysis revealed that CBD interacted with the serotonin receptors in our brain, which, in turn, helped to lower anxiety and depression levels. 

As the level of research on cannabis increases, It is now thought that it could potentially help with depression relief through a number of cannabinoids and terpenes contained within the plant that synergise through the Entourage Effect. 

The Best Marijuana Strains for Depression 

There are many strains that may help in curbing depression symptoms due to the chemical balance of cannabinoids and cannabis terpenes displayed in the cannabis plant. 

With research and user testimony indicating that medical marijuana has the potential to treat depression, many people have started using different marijuana strains as an alternative treatment for the condition. For beginners, it can be a bit daunting trying to understand the differences between indica strains, sativa strains and CBD strains. 

Indeed, understanding the type of cannabis strains best suited to your needs is vital when using medical marijuana so, to help you on your way, we have compiled a list of some of the best strains for treating depression.

Pineapple Express

An increasingly popular choice and one of the best strains for treating depression is the world-famous hybrid Pineapple Express. This wonderfully uplifting strain boasts the combination of effectiveness and flavour or its parents, Trainwreck and Hawaiian.

The heavy-hitting combination of Trainwreck and Hawaiian produces a wonderful Sativa dominant hybrid with a THC ratio somewhere between 17-20% with low CBD readings of less than 1%.

With a terpene profile that contains caryophyllene, limonene and myrcene, this hugely popular cannabis cup winner can help to energize the body, and improve productivity, making it an excellent strain to treat depression.

Blue Dream

A Sativa dominant hybrid, with high levels of THC, Blue Dream is thought to be one of the best strains for relaxing both mind and body which also makes it one of the best cannabis strains for depression. 

With a high THC ratio (approaching 20%) Blue Dream is one of the more potent strains and thought to be particularly effective in the treatment of stress and depression. Blue Dream ́s terpene profile shows high levels of limonene, pinene, and myrcene that may help to control mood disorders.

A cross of Blueberry with Haze, Blue Dream is a sativa strain that achieves full-body relaxation with some subtle cerebral stimulation. With a sweet berry aroma similar to that of its Blueberry parent, Blue Dream can help to treat depression without any heavy sedative effects. As such, Blue Dream is a popular daytime medicine for those looking for a little depression relief. 

Sour Diesel

Commonly known as Sour D, this fantastic hybrid strain has the potential to aid several stress disorders, including physical pain, and, depression and anxiety.

Another sativa strain, this time a  Sativa dominant hybrid that is said to have descended from Chemdog 91 and Super Skunk, Sour Diesel is rich in terpenes caryophyllene, myrcene, and limonene that lend itself to this strains peppery, citrus-like aroma and taste. This fast-acting behemoth can produce energising cerebral effects that have made Sour Diesel a legendary strain amongst cannabis enthusiasts and medical patients looking to treat mood disorders.

With a high THC ratio between 16 and 20%,  Sour Diesel has the potential to lift your mood and energy levels, making it a great cannabis strain that could provide a strong antidepressant effect for those suffering from depression. 

Jack Herer

A descendant of Shiva Skunk and Northern Lights #5. Jack Herer is a wildly popular hybrid strain that is famed for its uplifting qualities and antidepressant effect that is said to induce both happiness and creativity.

This type of strain, a Sativa dominant hybrid, is favoured by many for their stress-relieving effects as well as their balanced blend of sativa and indica effects.

Jack Herer’s THC ratio usually sits around 15 to 20%, with its dominant terpenes terpinolene, limonene and pinene thought to be particularly useful in boosting mood and focus. With a rich, piney, woody aroma, Jack Herer is a smooth yet potent strain and amongst seasoned marijuana users, remains one of the best strains for treating depression and reducing anxiety. 

Other strains worthy of a mention include OG Kush Seeds, Super Silver Haze Seeds and any of the classic Cookies strains which can all prove to be potentially effective in reducing the symptoms of depression and anxiety.

Indeed, the potential benefits of cannabis on the mind and body seem to be endless so If you ́re one of the millions suffering from depression and you’re interested in growing your own cannabis to help treat depression, please visit our growing community for more information on our huge selection of award-winning and popular strains for depression relief.

We have a vast range of seeds including sativa and indica strains, CBD strains, CBD oils and much more to choose from including popular strains like Mango Kush, Girl Scout Cookies and Northern lights.

Read More

Best seeds based on your preference

Refine your search

Page 1 / 7

    Yellow Snow

    Regular | Medicinal

    A frosty blend of lemon flavours and balanced but intense sensory effects, Yellow Snow cannabis seeds from the Archive Seedbank combine GSC and OG Kush genetics into a single high-powered indica-leaning hybrid. Offering impressive yields and a fast flowering period, Yellow Snow regular seeds could be the perfect choice for your next cannabis grow. 

    Regular
    Clear selection
    • Discrete shipping
    • Shipping the next working day
    • Cryptocurrencies accepted
    • Track & Trace available
    • Free Track & Trace for orders above € 100
    More Information

    Diesel Dough

    Regular | Medicinal

    Rev up your proverbial engines for Diesel Dough, a stimulating sativa-dominant strain from the famous Archive Seed Bank. Boasting impressive resin production, this potent powerhouse is definitely your go-to daytime strain to spark creativity and deliver a heavy head rush of energy.

    Regular
    Clear selection
    • Discrete shipping
    • Shipping the next working day
    • Cryptocurrencies accepted
    • Track & Trace available
    • Free Track & Trace for orders above € 100
    More Information

    Dank n Later

    Feminized | Medicinal

    These tantalising Dank n Later feminised cannabis seeds at our seed bank come from the fine minds at Dank Genetics. The seed company is well known for creating unique blends of marijuana strains, and this slightly indica leaning hybrid strain is no different.

    These tantalising Dank n Later feminised cannabis seeds come from the fine minds at Dank Genetics. The seeds co. is well known for creating unique blends of marijuana strains, and this slightly indica-leaning hybrid is no different.

    Feminized
    Clear selection
    • Discrete shipping
    • Shipping the next working day
    • Cryptocurrencies accepted
    • Track & Trace available
    • Free Track & Trace for orders above € 100
    More Information

    Headshot

    Feminized | Medicinal

    One of Sour Diesel’s favourite grandchildren, Headshot cannabis seeds come to our seed bank via the expert seeds creators at Dank Genetics. This indica-leaning, feminised marijuana strain is more than worthy of your attention, punching like a heavyweight and biting like a bulldog, as well as supplying a truly delicious kush, skunk, and diesel blend of flavours.

    Feminized
    Clear selection
    • Discrete shipping
    • Shipping the next working day
    • Cryptocurrencies accepted
    • Track & Trace available
    • Free Track & Trace for orders above € 100
    More Information

    Orangutan Titties

    A charmingly named, high THC, 50/50 hybrid from the popular breeders at Exotic Genetix seed co, Orangutan Titties cannabis seeds benefit from a fast flowering time and an easy to grow nature. When grown, these high THC, low CBD seeds produce orange and purple-hued buds, coated in sexy, pure white trichomes that provide a heady high.

    Feminized
    Clear selection
    • Discrete shipping
    • Shipping the next working day
    • Cryptocurrencies accepted
    • Track & Trace available
    • Free Track & Trace for orders above € 100
    More Information

    Grape Zkittlez

    Regular | Medicinal

    An indica-dominant cup winner that’s named for its candy flavoured appeal, Grape Zkittlez is a sugary sweet cannabis classic from Apothecary Genetics that really lets you taste the rainbow!   

    Regular
    Clear selection
    • Discrete shipping
    • Shipping the next working day
    • Cryptocurrencies accepted
    • Track & Trace available
    • Free Track & Trace for orders above € 100
    More Information

    Grape MAC

    Regular | Medicinal

    Born from two internationally renowned cannabis superstars, Grape MAC is a tasty and extra-resinous marijuana hybrid from the legendary breeders at Apothecary Genetics that offers balanced but potent effects, and a flavour profile that’s truly out of this world!

    Regular
    Clear selection
    • Discrete shipping
    • Shipping the next working day
    • Cryptocurrencies accepted
    • Track & Trace available
    • Free Track & Trace for orders above € 100
    More Information

    Beach Wedding

    Regular | Medicinal

    Sun, sea, and sand are all well and good, but why not make Beach Wedding – a tasty indica-dominant seed type from the strain hunters at the Oni Seeds company – your next one-stop destination for rest and relaxation?

    Regular
    Clear selection
    • Discrete shipping
    • Shipping the next working day
    • Cryptocurrencies accepted
    • Track & Trace available
    • Free Track & Trace for orders above € 100
    More Information

    Grape Kimbo Kush

    Regular | Medicinal

    The latest indica-dominant addition to the Apothecary Genetics ranks, Grape Kimbo Kush is a powerhouse hybrid with a fruity kush flavour and a knockout impact that’ll put you down for the count.

    Regular
    Clear selection
    • Discrete shipping
    • Shipping the next working day
    • Cryptocurrencies accepted
    • Track & Trace available
    • Free Track & Trace for orders above € 100
    More Information

    Pink Panties

    Regular | Medicinal

    Pink Panties is an indica-dominant cannabis strain that is notable for its high THC level, fast flowering time and vibrant dark green, purple-tinged buds. From the expert strain hunters at Apothecary Genetics, this impressive hybrid (available in regular seeds only) offers seriously potent yet heavenly smooth effects.

    Regular
    Clear selection
    • Discrete shipping
    • Shipping the next working day
    • Cryptocurrencies accepted
    • Track & Trace available
    • Free Track & Trace for orders above € 100
    More Information

    Dubb Breath

    Feminized | Medicinal

    One for the petrol heads and hydroponics enthusiasts, Dubb Breath, is an equally balanced, feminized cannabis blend from the Oni Seed co that crams together two fuel flavoured favourites into one delicious diesel hybrid. With a rapid flowering time and potent resin production, Dubb Breah is another welcome Oni seeds addition to our seeds bank. 

    Feminized
    Clear selection
    • Discrete shipping
    • Shipping the next working day
    • Cryptocurrencies accepted
    • Track & Trace available
    • Free Track & Trace for orders above € 100
    More Information

    Black Garlic

    Feminized | Medicinal

    Creatures of the night beware! Black Garlic is an indica-dominant Girl Scout Cookies hybrid from the Oni Seeds co. A welcome addition to the ever-growing MGS seeds bank, Black Garlic boasts a sour bite and tons of sticky resin – perfect for concentrate vampires of the cannabis community.

     

    Feminized
    Clear selection
    • Discrete shipping
    • Shipping the next working day
    • Cryptocurrencies accepted
    • Track & Trace available
    • Free Track & Trace for orders above € 100
    More Information

    Papaya Punch

    Regular | Medicinal

    Papaya Punch cannabis seeds are an intense, fruity offering available as regular seeds from the Oni Seed Co.

    A relatively new name to the marijuana world, this indica-dominant hybrid is still shrouded in some mystery. However, a fascinating genetic background has created plenty of buzz regarding this top shelf, high THC level strain. 

    Regular
    Clear selection
    • Discrete shipping
    • Shipping the next working day
    • Cryptocurrencies accepted
    • Track & Trace available
    • Free Track & Trace for orders above € 100
    More Information

    Strawpicanna

    Regular | Medicinal

    Take your tastebuds on a trip to flavour town with Strawpicanna – a sativa dominant hybrid cannabis strain from the Oni Seeds Co that blends Cookies and Kush genetics into a berry flavoured marijuana treat.

    Regular
    Clear selection
    • Discrete shipping
    • Shipping the next working day
    • Cryptocurrencies accepted
    • Track & Trace available
    • Free Track & Trace for orders above € 100
    More Information

    Hot Tropic

    Regular | Medicinal

    Sativa-dominant hybrid cannabis strain, Hot Tropic, is a fruity, exotic masterpiece from Oni Seeds Co. The result of combining Fire OG with Tropicanna Cookies F1, these regular seeds hail from impressive genetic stock, offering users a fabulously potent, top-shelf hybrid strain.

    Regular
    Clear selection
    • Discrete shipping
    • Shipping the next working day
    • Cryptocurrencies accepted
    • Track & Trace available
    • Free Track & Trace for orders above € 100
    More Information

Don’t worry, we handle your order discretely

To ensure this, we use plain 20x27 white bubble wrap envelopes without any visible labelling except for your adres and our return address.
Our company name will read as “Guru Trading BV”. No other company labels, receipts or any references to cannabis are included on the envelope.

Want to know more about our shipping?

Want to know more about our shipping?

At Guru we make sure your order is handled discreetly and with the utmost care and privacy.
Still not sure? Watch our video about our shipping procedure.

What our users say

This website was recommended to me, it was exactly what I was looking for. So much useful information, I could literally read for hours. This is now where I get my CBD oil and my purple punch seeds are growing nicely. They also have really unique and useful packaging for the seeds. Cool company!
siun mcfaden
siun mcfaden
19:01 19 Jun 19
Personalized customer service and updates to the status of the order. I would very much recommend Coffeeshop Guru. In addition, they carry specialized seeds for less that other shops. I am a very happy client.
April Fregd
April Fregd
11:30 06 Jul 19
Informative website. Products are delivered with care. I am very satisfied with my new Amnesia Haze seeds. Let them grow, Guru go go go!
Pieter Van Vliet
Pieter Van Vliet
14:50 24 Jun 19
I'm impressed with the website and the variety of products they stock. My order arrived in a very unique, stylish package that really made a good first impression about the quality of this company.
Jeroen Stapper
Jeroen Stapper
17:21 21 Jun 19
I like the fact they care about cannabis. I can see that in their packaging and the info they provide on the site. Good shop, will order from them again.
Robert Nijhout
Robert Nijhout
18:48 05 Jul 19

Latest Community contributions